Amlodipine 5 mg

Amlodipine 5 Mg Tablet is a prescription drug, available for use as Tablet. It is typically used for the treatment of High BP. Amlodipine 5 Mg Tablet also has some secondary and off-label uses. These are listed below. The optimal dosage of Amlodipine 5 Mg Tablet is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section. Some other side effects of Amlodipine 5 Mg Tablet have been listed ahead. Normally, these side effects of Amlodipine 5 Mg Tablet are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration. Amlodipine 5 Mg Tablet's effect during pregnancy is Severe and Unknown while nursing. In addition, Amlodipine 5 Mg Tablet's effects on the liver, heart and kidney are discussed below in the Amlodipine 5 Mg Tablet related warnings section. Individuals suffering from medical conditions like Low Blood Pressure (Hypotension), Coronary Artery Disease (CAD), Liver Disease must refrain from the use of Amlodipine 5 Mg Tablet since this can cause severe adverse effects. Other contraindications of Amlodipine 5 Mg Tablet have been discussed in the sections ahead. Besides this, Amlodipine 5 Mg Tablet may also have severe interaction with some medicines. A complete list of these interactions is gi...

Amlodipine Generic name: amlodipine [ am-LOE-di-peen] Brand names: Dosage forms: oral liquid (1 mg/mL), oral suspension (1 mg/mL), oral tablet (10 mg; 2.5 mg; 5 mg) Drug class: Medically reviewed by • • • • • • • What is amlodipine? Amlodipine belongs to a class of medications called calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. Amlodipine is used to treat certain types of Amlodipine controls chest pain by increasing the supply of blood to the heart. If taken regularly, this medicine controls chest pain, but it does not stop chest pain once it starts. Your doctor may prescribe a different medication to take when you have chest pain. Amlodipine is also used alone or in combination with other medicines to treat Warnings Before taking amlodipine, tell your doctor if you have congestive heart failure or liver disease. Drinking alcohol can further lower your blood pressure and may increase certain side effects of amlodipine. If you are being treated for high blood pressure, keep using amlodipine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Tell your doctor about all other heart or blood pressure medications yo...

Amlodipin là chất đối kháng ion calci và ức chế dòng ion calci đi vào tế bào cơ tim và cơ trơn. Cơ chế hạ huyết áp của amlodipin dựa trên tác dụng làm giãn trực tiếp cơ trơn mạch máu. Cơ chế chính xác làm giảm đau thắt ngực của amlodipin chưa được xác định hoàn toàn nhưng chủ yếu bằng hai tác động sau: Khả dụng sinh học của amlodipin khi uống khoảng 60 - 80% và không bị ảnh hưởng bởi thức ăn. Nồng độ đỉnh trong huyết tương đạt được sau khi uống liều khuyến cáo 6 đến 12 giờ. Nửa đời trong huyết tương từ 30 - 40 giờ. Nồng độ đỉnh trong huyết tương đạt 7 đến 8 ngày sau khi uống thuốc mỗi ngày 1 lần. Thể tích phân bố xấp xỉ 21 lít/ kg thể trọng và thuốc liên kết với protein - huyết tương cao (trên 98%). Độ thanh thải trong huyết tương tới mức bình thường vào khoảng 7 ml/ phút/ kg thể trọng do bài tiết chủ yếu thông qua chuyển hóa trong gan. Các chất chuyển hóa mất hoạt tính và bài tiết qua nước tiểu. Ở người, kinh nghiệm khi dùng quá liều do cố ý còn hạn chế. Các dữ liệu hiện có cho biết quá liều (> 100 mg) gây nên giãn mạch ngoại vi quá mức, dẫn đến hạ huyết áp toàn thân rõ rệt và có thể kéo dài. Triệu chứng hạ huyết áp do quá liều amlodipin cần biện pháp hỗ trợ tim mạch tích cực bao gồm kiểm tra thường xuyên chức năng tim và hô hấp, nâng cao tứ chi, theo dõi thể tích dịch tuần hoàn và lượng nước tiểu. Nếu không có chống chỉ định, chất co mạch có thể giúp phục hồi huyết áp. Tiêm vào tĩnh mạch calci gluconat có thể giúp đảo ngược lại tác động nghẽn kênh calci. Rửa dạ dày có th...

Amlodipine: 7 things you should know Medically reviewed by • • • • • • • 1. How it works • Amlodipine may be used to treat heart conditions such as angina and high blood pressure. • Amlodipine inhibits the influx of calcium ions across cardiac (heart) and smooth muscle causing relaxation of these muscles and dilation (widening). The exact way amlodipine works in angina is not known; however, experts believe it helps prevent spasm of the coronary artery and reduces how hard the heart has to work to pump blood around the body, lowering its oxygen requirements. Amlodipine does not change the levels of calcium in the blood. • Amlodipine belongs to a class of medicines called calcium channel blockers (sometimes called calcium channel antagonists). 2. Upsides • May be used for the treatment of high blood pressure (hypertension), alone or in combination with other agents for high blood pressure. • May be used as an ongoing treatment to relieve symptoms such as chest pain in people with chronic stable angina, or angina due to coronary artery spasm. Will not relieve acute episodes of angina (other medications such as sublingual nitroglycerin are used for this purpose). • In African Americans, calcium channel blockers such as amlodipine may be recommended over other types of heart medications (for example ACE inhibitors, ARBs) for the treatment of hypertension. • Appears to have little or no interaction with grapefruit or grapefruit products or antacids. • Can improve a person's tol...

If you have certain heart conditions, your doctor may prescribe amlodipine oral tablet for you. It’s a prescription drug that’s used to treat For high blood pressure and CAD, you may take amlodipine oral tablets with other drugs. To learn more about these conditions and how amlodipine is used to treat them, see the “ Amlodipine oral tablet basics Amlodipine oral tablet contains the active drug amlodipine besylate. This drug is classified as a You’ll take amlodipine oral tablets by swallowing them. Note: Amlodipine also comes as an oral suspension (a type of liquid mixture). But only the oral tablet is described in this article. If you’d like to learn about amlodipine’s other form, talk with your doctor or pharmacist. Amlodipine oral tablet brand-name versions Amlodipine oral tablet is a Note: The oral suspension form of amlodipine has another brand-name drug version. To learn about this other version, talk with your doctor or pharmacist. Amlodipine oral tablet is a If you’re interested in using Norvasc instead of amlodipine oral tablet, talk with your doctor. They can tell you if Norvasc comes in strengths that can be used for your condition. If you have insurance, you’ll also need to check whether your plan will cover Norvasc. To learn more about how generics compare with brand-name drugs, see Like most drugs, amlodipine oral tablet may cause mild or serious side effects. The lists below describe some of the more common side effects. These lists don’t include all possible...

Norvasc helps lower blood pressure by triggering the dilation of blood vessels. The increased blood flow, in turn, intensifies the pressure within smaller blood vessels, causing excess fluids to seep through the walls of the vessels into surrounding tissues. Treatment If you experience edema while taking Norvasc, do not stop treatment until you speak with your healthcare provider. In some cases, you may be placed on a diuretic ("water pill") to reduce the swelling. Or, the Norvasc dose may be reduced. Summary Norvasc (amlodipine besylate) is a type of drug called a calcium channel blocker used to treat high blood pressure and angina. One of the more common side effects of Norvasc is edema, or the abnormal swelling of tissue due to the build-up of fluid. Although the ankles and feet are most commonly affected, the hands and lower legs may also experience swelling. If edema occurs while taking Norvasc, call your healthcare provider. You may be switch to another calcium channel blocker or a different class of blood pressure medication. Or, the Norvasc dose may simply be reduced to see if that helps. Never stop or alter treatment without first speaking to your healthcare provider. • Bulsara KG, Cassagnol M. • Galappatthy P, Waniganayake YC, Sabeer MI, Wijethunga TJ, Galappatthy GK, Ekanayaka RA. BMC Cardiovasc Disord. 2016;16(1):168. doi:10.1186/s12872-016-0350-z • Makri OE, Georgalas I, Georgakopoulos CD. • Morrison RT. • Miyoshi K, Okura T, Nagao T, Masanori J, Irita J, Higa...

Amlodipine’s possible side effects are described below. More common side effects The more common side effects that can occur with amlodipine include: • swelling of your legs or ankles • • feeling sleepy • abdominal pain • nausea • dizziness • hot or warm feeling in your face (flushing) • very fast heart rate (palpitations) If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. Serious side effects Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following: • Low blood pressure. Symptoms can include: • severe dizziness • lightheadedness • fainting • More chest pain or a • chest pain or discomfort • upper body discomfort • shortness of breath • breaking out in a cold sweat • unusual tiredness • nausea • lightheadedness Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history. Amlodipine is a prescription drug. It comes as a tablet you take by mouth. Amlodipine is available as the brand-name dru...

Dosage Forms Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Suspension, Oral, as benzoate: Katerzia: 1 mg/mL (150 mL) [contains polysorbate 80, sodium benzoate] Tablet, Oral: Norvasc: 10 mg Generic: 10 mg Tablet, Oral, as besylate: Norvasc: 2.5 mg, 5 mg Generic: 2.5 mg, 5 mg Pharmacology Mechanism of Action Inhibits calcium ion from entering the “slow channels” or select voltage-sensitive areas of vascular smooth muscle and myocardium during depolarization, producing a relaxation of coronary vascular smooth muscle and coronary vasodilation; increases myocardial oxygen delivery in patients with vasospastic angina. Amlodipine directly acts on vascular smooth muscle to produce peripheral arterial vasodilation reducing peripheral vascular resistance and blood pressure. Pharmacokinetics/Pharmacodynamics Absorption Well absorbed (Meredith 1992) Distribution Mean V d: Children >6 years: Similar to adults on a mg per kg basis; Note: Weight-adjusted V d in younger children (6 years of age is similar to adults; Note: Weight-adjusted clearance in younger children (5 mg daily have not been fully studied. In a randomized, placebo-controlled trial of amlodipine in children (n=268; mean age: 12.1 years; range: 6 to 16 years), a significant reduction in systolic blood pressure (compared to placebo) was observed in both the 2.5 mg once daily and the 5 mg once daily amlodipine groups. The authors recommend an initial d...

Norvasc helps lower blood pressure by triggering the dilation of blood vessels. The increased blood flow, in turn, intensifies the pressure within smaller blood vessels, causing excess fluids to seep through the walls of the vessels into surrounding tissues. Treatment If you experience edema while taking Norvasc, do not stop treatment until you speak with your healthcare provider. In some cases, you may be placed on a diuretic ("water pill") to reduce the swelling. Or, the Norvasc dose may be reduced. Summary Norvasc (amlodipine besylate) is a type of drug called a calcium channel blocker used to treat high blood pressure and angina. One of the more common side effects of Norvasc is edema, or the abnormal swelling of tissue due to the build-up of fluid. Although the ankles and feet are most commonly affected, the hands and lower legs may also experience swelling. If edema occurs while taking Norvasc, call your healthcare provider. You may be switch to another calcium channel blocker or a different class of blood pressure medication. Or, the Norvasc dose may simply be reduced to see if that helps. Never stop or alter treatment without first speaking to your healthcare provider. • Bulsara KG, Cassagnol M. • Galappatthy P, Waniganayake YC, Sabeer MI, Wijethunga TJ, Galappatthy GK, Ekanayaka RA. BMC Cardiovasc Disord. 2016;16(1):168. doi:10.1186/s12872-016-0350-z • Makri OE, Georgalas I, Georgakopoulos CD. • Morrison RT. • Miyoshi K, Okura T, Nagao T, Masanori J, Irita J, Higa...

Amlodipine 5 Mg Tablet is a prescription drug, available for use as Tablet. It is typically used for the treatment of High BP. Amlodipine 5 Mg Tablet also has some secondary and off-label uses. These are listed below. The optimal dosage of Amlodipine 5 Mg Tablet is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section. Some other side effects of Amlodipine 5 Mg Tablet have been listed ahead. Normally, these side effects of Amlodipine 5 Mg Tablet are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration. Amlodipine 5 Mg Tablet's effect during pregnancy is Severe and Unknown while nursing. In addition, Amlodipine 5 Mg Tablet's effects on the liver, heart and kidney are discussed below in the Amlodipine 5 Mg Tablet related warnings section. Individuals suffering from medical conditions like Low Blood Pressure (Hypotension), Coronary Artery Disease (CAD), Liver Disease must refrain from the use of Amlodipine 5 Mg Tablet since this can cause severe adverse effects. Other contraindications of Amlodipine 5 Mg Tablet have been discussed in the sections ahead. Besides this, Amlodipine 5 Mg Tablet may also have severe interaction with some medicines. A complete list of these interactions is gi...