Diclofenac gel ip 1.0 w/w

WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events • Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use [ see Warnings and Precautions • Diclofenac sodium topical gel is contraindicated in the setting of coronary artery bypass graft (CABG) surgery [ see Contraindications ( Gastrointestinal Bleeding, Ulceration, and Perforation • NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events [ see Warnings and Precautions ( Indications and Usage for Diclofenac Gel Related/similar drugs Diclofenac Gel Dosage and Administration [see Warnings and Precautions ( Apply diclofenac sodium topical gel gently to lesion areas twice daily to adequately cover each lesion. Use 0.5 g of gel (pea size) on each 5 cm x 5 cm lesion site. The recommended duration of therapy is from 60 days to 90 days. Complete healing of the lesion(s) or optimal therapeutic effect may not be evident for up to 30 days following cessation o...

Warning • This medicine may raise the risk of heart and blood vessel problems like heart attack and stroke. These effects can be deadly. The risk may be greater if you have heart disease or risks for heart disease. However, it can also be raised even if you do not have heart disease or risks for heart disease. The risk can happen within the first weeks of using diclofenac gel (1%) and may be greater with higher doses or long-term use. Do not use diclofenac gel (1%) right before or after bypass heart surgery. • This medicine may raise the chance of severe and sometimes deadly stomach or bowel problems like ulcers or bleeding. The risk is greater in older people, and in people who have had stomach or bowel ulcers or bleeding before. These problems may occur without warning signs. Uses of Diclofenac Gel: • It is used to treat arthritis. Related/similar drugs What do I need to tell my doctor BEFORE I take Diclofenac Gel? • If you have an allergy to • If you have an allergy to • If you are allergic to diclofenac gel (1%); any part of diclofenac gel (1%); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. • If you have ever had • If you have any of these health problems: • If you have had a recent • If you are having trouble getting pregnant or you are having your fertility checked. • If you are pregnant or may be pregnant. Do not take diclofenac gel (1%) if you are in the third trimester of pregnancy. You may also need to avoid ...