Phenylephrine hydrochloride & chlorpheniramine maleate

Phenylephrine: 7 things you should know Medically reviewed by • • • • • • • 1. How it works • Phenylephrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. Injectable forms may also be used to increase blood pressure. • Phenylephrine works by directly stimulating alpha-1 adrenergic receptors in the arteries causing vasoconstriction (narrowing of the blood vessels). This reduces nasal congestion by preventing fluid from draining from the blood vessels into the tissues lining the nasal passages. Phenylephrine may also cause dose-dependent increases in blood pressure and reductions in heart rate and cardiac output (particularly in people with preexisting cardiac dysfunction) by increasing systemic vascular resistance. • Phenylephrine belongs to the class of medicines known as nasal decongestants. It may also be called a vasopressor or a selective alpha-1-adrenergic receptor agonist. 2. Upsides • Tablets, chewable tablets, liquid and nasal preparations of phenylephrine are used to treat nasal and sinus congestion. • Can also relieve congestion in the eustachian tubes (the tubes that drain fluid from the inner ears). • Phenylephrine for injection may be used in the treatment of low blood pressure, shock, or supraventricular tachycardia. • May be used off-label for ischemic priapism that persists following aspiration or irrigation or for low blood pressure in people with obstructive hypertrophic cardiomyopathy. • There are...

Phenylephrine Generic name: phenylephrine (oral) [ FEN-il-EFF-rin] Brand names: Despec-SF, Biorphen, Lusonal, Sudafed PE Quick Dissolve, Sudafed PE Extra Strength, Triaminic Thin Strips Nasal Congestion, Triaminic Toddler Congestion Thin Strips, Nasop12, Dimetapp Cold Drops, Triaminic Thin Strips Cold, Triaminic Thin Strips Infant Decongestant, Dimetapp Children's Cold and Allergy, Phenyl-T, PediaCare Children's Decongestant, Sudafed PE Children's Nasal Decongestant, Vazculep, Sudafed PE Congestion, Phenylephrine Hydrochloride (Eqv-Vazculep) Dosage forms: oral liquid (2.5 mg/5 mL), oral tablet (10 mg), oral tablet, chewable, extended release (tannate 10 mg), oral tablet, disintegrating (10 mg) Drug classes: • • • • • • • Before taking this medicine Do not use phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. You should not use phenylephrine if you are allergic to it. Ask a doctor or pharmacist if this medicine is safe to use if you have: • heart disease, • diabetes; • a thyroid disorder; • an • any drug allergies. Ask a doctor before using this medicine if you are pregnant or breast-feeding. The liquid form of this medicine may contain phenylalanine. Check the medication label if you have How should I take phenylephrine? Use exactly as directed on the label, or as prescribed ...

Pseudoephedrine and phenylephrine are both nasal decongestants but can have different side effects. You can only purchase pseudoephedrine from pharmacy staff and have to show your ID. You may know pseudoephedrine and phenylephrine from their use in Sudafed products. Sudafed contains pseudoephedrine, while Sudafed PE contains phenylephrine. The drugs are also available in several combinations with other over-the-counter cough and cold medications. These drugs are both nasal decongestants. They’re used for short-term relief of congestion and pressure in the sinuses and nasal passages caused by the common cold, hay fever, or other allergies. If you’re ready to breathe easier, check out this comparison of pseudoephedrine and phenylephrine. Psuedoephedrine Phenylephrine What’s the brand name version? Sudafed Sudafed PE Is a generic version available? yes yes Why is it used? short-term relief of sinus or nasal congestion and pressure short-term relief of sinus or nasal congestion and pressure Does it require a prescription? no no Are there special requirements for purchase? yes no What form(s) does it come in? • oral tablet • oral liquid • oral extended-release (long-acting) tablets, 12-hour and 24-hour forms • oral tablet • oral liquid • nasal spray What are the strengths? • 30 mg • 60 mg • 120 mg • 3–6 mg/mL • Tablets: 5-10 mg • Oral Liquid: 0.5 – 2.5mg/mL • Nasal Spray 0.125 -1% How often should I take it? • oral tablet or liquid: every 4–6 hours • 12-hour extended-release ta...

Phenylephrine nasal Generic name: phenylephrine nasal [ FEN-il-EFF-rin] Brand names: 4-Way, Sinex Nasal Spray, Alconefrin-12, Nostril Nasal Decongestant, Rhinall, Neo-Synephrine Extra Strength Nasal, Neo-Synephrine Mild Nasal, 4-Way Menthol, Neo-Synephrine Cold and Sinus Regular Strength, Neo-Synephrine Cold and Sinus Extra Strength, Neo-Synephrine Cold and Sinus Mild Strength Dosage forms: nasal drops (0.125%), nasal solution (1%), nasal spray (0.25%; 0.5%; 1%) Drug class: • • • • • • What is phenylephrine nasal? Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause Phenylephrine nasal is used to treat nasal congestion and sinus pressure caused by Phenylephrine nasal may also be used for purposes not listed in this medication guide. Before taking this medicine You should not use phenylephrine nasal if you are allergic to it. Do not use phenylephrine nasal if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially: • heart disease, heart rhythm disorder; • • diabetes; • • a thyroid disorder; or • an It is not known whether phenylephrine nasal will harm an unborn baby. Do not use this medicine without a doctor's advice if y...

If you are using the over-the-counter product, read and follow all directions on the product package before taking this Take this medication by If you are using the liquid, carefully measure your prescribed dose using a medication-measuring device or spoon. Do not use a household spoon because you may not get the correct dose. If you are using chewable tablets, chew each tablet thoroughly before swallowing. If you are using a product made to dissolve in the The dosage is based on your age. Do not increase your dose or take this medication more often than directed without your doctor's approval. Improper use (abuse) of this medication may result in serious harm (such as If your symptoms worsen or do not improve after 7 days, if you develop fever/chills, or if you think you may have a serious medical problem, get medical help right away. Mild This product may reduce If your doctor has directed you to use this Tell your doctor right away if you have any serious side effects, including: fast/irregular heartbeat, severe/uncontrolled shaking, difficulty urinating, A very serious This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-2...

Key:SONNWYBIRXJNDC-VIFPVBQESA-N Y Phenylephrine is a 1-adrenergic receptor Common side effects when taken by mouth or injected include nausea, vomiting, headache, and anxiety. Phenylephrine was patented in 1927 and came into medical use in 1938. Medical uses [ ] Decongestant [ ] Phenylephrine is used as an alternative to A 2007 meta-analysis concluded that the evidence for its effectiveness is insufficient, Two studies published in 2009, examined the effects of phenylephrine on symptoms of Pseudoephedrine was previously much more commonly available in the United States, however, provisions of the [ citation needed] Hemorrhoids [ ] Pupil dilation [ ] "Prefrin" redirects here. For the iron supplement, see Phenylephrine is used as an eye drop to dilate the pupil to facilitate visualization of the retina. It is often used in combination with Intraocular bleeding [ ] Phenylephrine has been used as an intracameral injection into the anterior chamber of the eye to arrest intraocular bleeding occurring during cataract and glaucoma surgery. Vasopressor [ ] Phenylephrine is commonly used as a Because of its vasoconstrictive effect, phenylephrine can cause severe Phenylephrine hydrochloride at 0.25% is used as a vasoconstrictor in some Priapism [ ] Phenylephrine is used to treat Side effects [ ] Phenylephrine may cause side effects such as headache, Heart [ ] The primary side effect of phenylephrine is Other [ ] Phenylephrine is pregnancy category C. Due to the lack of studies done i...

What is this medication? PHENYLEPHRINE (fen il EF rin) treats a runny or stuffy nose. It may also be used to treat sinus congestion and pressure. It works by decreasing swelling in the nose, making it easier to breathe. It belongs to a group of medications called decongestants. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Sudafed PE, Sudafed PE Congestion, Sudafed PE Sinus Congestion, Sudogest PE What should I tell my care team before I take this medication? They need to know if you have any of the following conditions: • Diabetes • Heart disease • High blood pressure • Prostate problems • Taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days • Thyroid disease • Trouble passing urine or change in the amount of urine • An unusual or allergic reaction to phenylephrine, other decongestants, other medications, foods, dyes, or preservatives • Pregnant or trying to get pregnant • Breast-feeding How should I use this medication? Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take this medication with food, water, or milk to prevent stomach upset. Take your medication at regular intervals. Do not take it more often than directed. Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as 6 years old for selected conditions, precautions do...

Description and Brand Names Drug information provided by: US Brand Name • Neo-Synephrine • Nostril • Pretz-D • Rhinall • Tur-Bi-Cal • Vicks Sinex Descriptions Phenylephrine is used for the temporary relief of congestion or stuffiness in the nose caused by hay fever or other allergies, colds, or sinus trouble. It may also be used in ear infections to relieve congestion. This medicine may also be used for other conditions as determined by your doctor. This medicine is available without a prescription. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects . This product is available in the following dosage forms: • Solution • Spray • Portions of this document last updated: June 01, 2023 Copyright: © Merative US L.P. 1973, 2023. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. • •

Description and Brand Names Drug information provided by: US Brand Name • Neo-Synephrine • Nostril • Pretz-D • Rhinall • Tur-Bi-Cal • Vicks Sinex Descriptions Phenylephrine is used for the temporary relief of congestion or stuffiness in the nose caused by hay fever or other allergies, colds, or sinus trouble. It may also be used in ear infections to relieve congestion. This medicine may also be used for other conditions as determined by your doctor. This medicine is available without a prescription. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects . This product is available in the following dosage forms: • Solution • Spray • Portions of this document last updated: June 01, 2023 Copyright: © Merative US L.P. 1973, 2023. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. • •

Pseudoephedrine and phenylephrine are both nasal decongestants but can have different side effects. You can only purchase pseudoephedrine from pharmacy staff and have to show your ID. You may know pseudoephedrine and phenylephrine from their use in Sudafed products. Sudafed contains pseudoephedrine, while Sudafed PE contains phenylephrine. The drugs are also available in several combinations with other over-the-counter cough and cold medications. These drugs are both nasal decongestants. They’re used for short-term relief of congestion and pressure in the sinuses and nasal passages caused by the common cold, hay fever, or other allergies. If you’re ready to breathe easier, check out this comparison of pseudoephedrine and phenylephrine. Psuedoephedrine Phenylephrine What’s the brand name version? Sudafed Sudafed PE Is a generic version available? yes yes Why is it used? short-term relief of sinus or nasal congestion and pressure short-term relief of sinus or nasal congestion and pressure Does it require a prescription? no no Are there special requirements for purchase? yes no What form(s) does it come in? • oral tablet • oral liquid • oral extended-release (long-acting) tablets, 12-hour and 24-hour forms • oral tablet • oral liquid • nasal spray What are the strengths? • 30 mg • 60 mg • 120 mg • 3–6 mg/mL • Tablets: 5-10 mg • Oral Liquid: 0.5 – 2.5mg/mL • Nasal Spray 0.125 -1% How often should I take it? • oral tablet or liquid: every 4–6 hours • 12-hour extended-release ta...