Cetirizine pediatric dose mg/kg

DESCRIPTION Piperazine antihistamine; active metabolite of hydroxyzine; considered "low-sedating" Used orally for allergic rhinitis and chronic idiopathic urticaria in adults and pediatric patients; intravenous injection used for acute urticaria Ophthalmic solution used for ocular pruritus due to allergic conjunctivitis COMMON BRAND NAMES All Day Allergy, All Day Allergy Children's, Allergy Relief, Children's Allergy Relief, PediaCare Children's Allergy, Quzyttir, ZERVIATE, Zyrtec, Zyrtec Chewable, Zyrtec Children's, Zyrtec Children's Allergy, ZYRTEC Children's Dye Free, Zyrtec Children's Hives, Zyrtec Dissolve, ZYRTEC Dye Free, Zyrtec Hives Relief, Zyrtec Liquid Gel, Zyrtec Pre-Filled Spoons HOW SUPPLIED All Day Allergy Children's/Cetirizine/Cetirizine Hydrochloride/Children's Allergy Relief/PediaCare Children's Allergy/Zyrtec/Zyrtec Children's/Zyrtec Children's Allergy/Zyrtec Children's Hives/Zyrtec Pre-Filled Spoons Oral Sol: 1mg, 1mL, 5mg, 5mL All Day Allergy Children's/Cetirizine/Cetirizine Hydrochloride/Zyrtec/Zyrtec Chewable/Zyrtec Children's/ZYRTEC Children's Dye Free/ZYRTEC Dye Free Oral Tab Chew: 2.5mg, 5mg, 10mg All Day Allergy/Allergy Relief/Cetirizine/Cetirizine Hydrochloride/Zyrtec/Zyrtec Hives Relief Oral Tab: 5mg, 10mg Cetirizine Ophthalmic Sol: 1mL, 2.4mg Cetirizine/Cetirizine Hydrochloride/Zyrtec Liquid Gel Oral Cap: 10mg Quzyttir Intravenous Inj: 1mL, 10mg Zyrtec Children's Allergy Oral Tab Orally Dis: 10mg Geriatric Adults 5 to 10 mg orally once daily; ...

Answer: I have seen a lot of urticaria, but don’t ever remember a case of cholinergic urticaria in an infant. I find that viral infections are a frequent cause of urticaria in infants. I feel your question needs more information. Do the hives appear to be triggered by temperature change? Cooling, like after a bath? Is there associated fever? Is there evidence of urticaria pigmentosa? Was there evidence of a precipitating viral infection? Back to your question. Estell Simons published a nice paper in JACI (1) reporting Cetirizine 0.25 mg/kg was a safe and effective dose in infants 6 to 11 months old. 1) Simons FE, Silas P, Portnoy JM, Catuogno J, Chapman D, Olufade AO, Pharmd. Safety of cetirizine in infants 6 to 11 months of age: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol. 2003 Jun;111(6):1244-8 I hope you found this helpful. Respectfully submitted Jeffrey G Demain, MD, FAAAAI

Adult: For symptomatic relief of seasonal and perennial allergic rhinitis; chronic idiopathic urticaria: 10 mg once daily. Child: 6-12 years 5 mg bid; >12 years Same as adult dose. Treatment and dosing recommendations may vary among individual products and between countries (refer to specific product guidelines). Eye disorders: Decreased visual acuity, ocular hyperaemia (ophth soln). Gastrointestinal disorders: Abdominal pain, dry mouth, nausea, diarrhoea, vomiting. General disorders and administration site conditions: Fatigue, local pain at instillation site (ophth). Nervous system disorders: Dizziness, headache, somnolence. Respiratory, thoracic and mediastinal disorders: Pharyngitis, rhinitis, epistaxis, bronchospasm. Description: Cetirizine, a piperazine derivative and metabolite of hydroxyzine, is an antihistamine which competitively and selectively inhibits H 1 receptors in the gastrointestinal tract, blood vessels, and respiratory tract. Onset: Suppression of skin wheal and flare: 20-60 minutes. Duration: Suppression of skin wheal and flare: ≥24 hours. Pharmacokinetics: Absorption: Rapidly absorbed from the gastrointestinal tract. Decreased rate of absorption with food. Time to peak plasma concentration: Approx 1 hour. Distribution: Enters breast milk. Volume of distribution: 0.56 L/kg. Plasma protein binding: 93%. Metabolism: Metabolised limitedly in the liver. Excretion: Mainly via urine (50% as unchanged drug); faeces (10%). Elimination half-life: 8 hours. Anon. ...

Cetirizine is a second-generation antihistamine, derived from the metabolism of hydroxyzine, highly specific for the H1 receptors, and with marked antiallergic properties. Although its history began more than 30Â years ago, it remains one of the most used drugs in children with a leading role in the medical care of children with allergic diseases. Cetirizine use is licensed for paediatric patients for the treatment of allergic rhinitis, and chronic spontaneous urticaria, in Europe in children older than 2Â years old and in the USA in children older than 6Â months old. This review provides a practical update on the use of cetirizine in children and adolescents. Cetirizine is a second-generation antihistamine derived from the metabolism of hydroxyzine, with high specificity for the H1 receptors and antiallergic properties [ Nowadays, cetirizine use is licensed for children and adolescents for the treatment of allergic rhinitis and chronic spontaneous urticaria (CSU); children should be older than 2Â years old, although the US Food and Drug Administration (FDA) licensed cetirizine also for children aged over 6Â months [ This review summarizes the evidence regarding the 30-year-history of cetirizine. The use of the drug during pregnancy and lactation will also be evaluated. Full size table An original report published in 2017 showed that the use of antihistamines is associated with severe and unexpected adverse drug reactions (ADRs), and 400 patients had a fatal outcome. More ...

Adult: For symptomatic relief of seasonal and perennial allergic rhinitis; chronic idiopathic urticaria: 10 mg once daily. Child: 6-12 years 5 mg bid; >12 years Same as adult dose. Treatment and dosing recommendations may vary among individual products and between countries (refer to specific product guidelines). Eye disorders: Decreased visual acuity, ocular hyperaemia (ophth soln). Gastrointestinal disorders: Abdominal pain, dry mouth, nausea, diarrhoea, vomiting. General disorders and administration site conditions: Fatigue, local pain at instillation site (ophth). Nervous system disorders: Dizziness, headache, somnolence. Respiratory, thoracic and mediastinal disorders: Pharyngitis, rhinitis, epistaxis, bronchospasm. Description: Cetirizine, a piperazine derivative and metabolite of hydroxyzine, is an antihistamine which competitively and selectively inhibits H 1 receptors in the gastrointestinal tract, blood vessels, and respiratory tract. Onset: Suppression of skin wheal and flare: 20-60 minutes. Duration: Suppression of skin wheal and flare: ≥24 hours. Pharmacokinetics: Absorption: Rapidly absorbed from the gastrointestinal tract. Decreased rate of absorption with food. Time to peak plasma concentration: Approx 1 hour. Distribution: Enters breast milk. Volume of distribution: 0.56 L/kg. Plasma protein binding: 93%. Metabolism: Metabolised limitedly in the liver. Excretion: Mainly via urine (50% as unchanged drug); faeces (10%). Elimination half-life: 8 hours. Anon. ...

Answer: I have seen a lot of urticaria, but don’t ever remember a case of cholinergic urticaria in an infant. I find that viral infections are a frequent cause of urticaria in infants. I feel your question needs more information. Do the hives appear to be triggered by temperature change? Cooling, like after a bath? Is there associated fever? Is there evidence of urticaria pigmentosa? Was there evidence of a precipitating viral infection? Back to your question. Estell Simons published a nice paper in JACI (1) reporting Cetirizine 0.25 mg/kg was a safe and effective dose in infants 6 to 11 months old. 1) Simons FE, Silas P, Portnoy JM, Catuogno J, Chapman D, Olufade AO, Pharmd. Safety of cetirizine in infants 6 to 11 months of age: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol. 2003 Jun;111(6):1244-8 I hope you found this helpful. Respectfully submitted Jeffrey G Demain, MD, FAAAAI

DESCRIPTION Piperazine antihistamine; active metabolite of hydroxyzine; considered "low-sedating" Used orally for allergic rhinitis and chronic idiopathic urticaria in adults and pediatric patients; intravenous injection used for acute urticaria Ophthalmic solution used for ocular pruritus due to allergic conjunctivitis COMMON BRAND NAMES All Day Allergy, All Day Allergy Children's, Allergy Relief, Children's Allergy Relief, PediaCare Children's Allergy, Quzyttir, ZERVIATE, Zyrtec, Zyrtec Chewable, Zyrtec Children's, Zyrtec Children's Allergy, ZYRTEC Children's Dye Free, Zyrtec Children's Hives, Zyrtec Dissolve, ZYRTEC Dye Free, Zyrtec Hives Relief, Zyrtec Liquid Gel, Zyrtec Pre-Filled Spoons HOW SUPPLIED All Day Allergy Children's/Cetirizine/Cetirizine Hydrochloride/Children's Allergy Relief/PediaCare Children's Allergy/Zyrtec/Zyrtec Children's/Zyrtec Children's Allergy/Zyrtec Children's Hives/Zyrtec Pre-Filled Spoons Oral Sol: 1mg, 1mL, 5mg, 5mL All Day Allergy Children's/Cetirizine/Cetirizine Hydrochloride/Zyrtec/Zyrtec Chewable/Zyrtec Children's/ZYRTEC Children's Dye Free/ZYRTEC Dye Free Oral Tab Chew: 2.5mg, 5mg, 10mg All Day Allergy/Allergy Relief/Cetirizine/Cetirizine Hydrochloride/Zyrtec/Zyrtec Hives Relief Oral Tab: 5mg, 10mg Cetirizine Ophthalmic Sol: 1mL, 2.4mg Cetirizine/Cetirizine Hydrochloride/Zyrtec Liquid Gel Oral Cap: 10mg Quzyttir Intravenous Inj: 1mL, 10mg Zyrtec Children's Allergy Oral Tab Orally Dis: 10mg Geriatric Adults 5 to 10 mg orally once daily; ...

Cetirizine is a second-generation antihistamine, derived from the metabolism of hydroxyzine, highly specific for the H1 receptors, and with marked antiallergic properties. Although its history began more than 30Â years ago, it remains one of the most used drugs in children with a leading role in the medical care of children with allergic diseases. Cetirizine use is licensed for paediatric patients for the treatment of allergic rhinitis, and chronic spontaneous urticaria, in Europe in children older than 2Â years old and in the USA in children older than 6Â months old. This review provides a practical update on the use of cetirizine in children and adolescents. Cetirizine is a second-generation antihistamine derived from the metabolism of hydroxyzine, with high specificity for the H1 receptors and antiallergic properties [ Nowadays, cetirizine use is licensed for children and adolescents for the treatment of allergic rhinitis and chronic spontaneous urticaria (CSU); children should be older than 2Â years old, although the US Food and Drug Administration (FDA) licensed cetirizine also for children aged over 6Â months [ This review summarizes the evidence regarding the 30-year-history of cetirizine. The use of the drug during pregnancy and lactation will also be evaluated. Full size table An original report published in 2017 showed that the use of antihistamines is associated with severe and unexpected adverse drug reactions (ADRs), and 400 patients had a fatal outcome. More ...