Sitagliptin / metformin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage,.

DAPAGLIFLOZIN; METFORMIN (DAP a gli FLOE zin; met FOR min) treats type 2 diabetes. It works by decreasing your blood sugar (glucose). Changes to diet and exercise are often combined with this medication. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

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Metformin is primarily used to treat type 2 diabetes by bringing blood sugar to a healthy range, although it doesn’t cure the disease. Most side effects are mild, though some can require.

Take metformin with a meal, unless your doctor tells you otherwise. Some forms of metformin are taken only once daily with the evening meal. Follow your doctor's instructions. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Measure liquid medicine carefully. Shake the oral suspension before you measure a dose. Use the.

Metformin has the potential to cause weight loss via several mechanisms, with appetite control at center stage. Metformin improves the body's response to the hormones insulin and leptin, which in turn decreases appetite, and also causes a cascade of reactions in the central nervous system that work to reduce hunger.

For patients not on an antihyperglycemic agent at study entry, mean reductions from baseline in A1C were: sitagliptin 100 mg once daily, -1.1%; metformin HCl 500 mg bid, -1.1%; metformin HCl 1000 mg bid, -1.2%; sitagliptin 50 mg bid with metformin HCl 500 mg bid, -1.6%; sitagliptin 50 mg bid with metformin HCl 1000 mg bid, -1.9%; and for.

For oral dosage form (immediate-release tablets): For patients taking metformin alone: Adults—At first, 50 milligrams (mg) of sitagliptin, plus the dose of metformin already being taken, 2 times per day. Your doctor may gradually increase your dose until your blood sugar is controlled. If you are taking 850 mg of metformin 2 times per day.

This medication is a combination of 2 drugs: dapagliflozin and metformin. It is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes..

Dapagliflozin and metformin combination is used together with proper diet and exercise to treat type 2 diabetes. It is also used to lower the risk of hospitalization for heart failure in patients with type 2 diabetes and cardiovascular (heart or blood vessel) disease or multiple cardiovascular risk factors.

For patients taking metformin HCl immediate-release 850 mg twice daily or 1000 mg twice daily, the recommended starting dose of JANUMET XR is two 50 mg sitagliptin and 1000 mg metformin HCl extended-release tablets taken together once daily. Maintain the same total daily dose of sitagliptin and metformin when changing between JANUMET.

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